ChromSword
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Method development with ChromSword according to ICH
Q14 guidelines and AQbD approach
Develop chromatographic methods faster and more efficiently using ChromSword’s advanced simulation and optimization tools.

What is ChromSwordAuto ?
ChromSwordAuto® is advanced chromatographic software enabling rapid and fully automated development of liquid chromatography methods (HPLC/UHPLC). It operates with minimal experimental input or in a fully unattended mode, significantly reducing manual trial-and-error.
Why Choose ChromSword ?
Faster Development
Reduce method development by 50-80 %
Reduce Cost
Minimize experimental runs and solvent consumptioon
Better Accuracy
Eliminate human error through automated decision-making
Expert- Level Results
Reproduce expert chromatographer strategies
How ChromSword Works ?
ChromSword Scout
Rapid column and solvent screening
ChromSword Developer (On-line)
Direct instrument control and optimization
ChromSword Offline
Simulation-based improvement of separations
ChromSword AutoRobust
Automated method improvement and robustness
Robustness Evaluation
Organic modifier composition, gradient profile, column temperature, flow rate,
equibration time, injection volume, wavelength, ph.
column batch.
Key Benefits
- 50-80% faster method development
- Reduced solvent and column consumption
- Increased reproducibility and robustness
- Reduced dependancy on expert users
Applications
- Pharmaceutical R&D​
- Quality Control laborataries
- Method transfer
- Impurity profiling
- Complex mixtures
- Small molecules
- Biomolecules
LC Instrument Control
Agilent Technologies (1100, 1200, 1260, 1290)
Thermo (Ultimate 3000, Vanquish)
Hitachi (Chromaster, Ultra testing using DoE with reporting)
Waters (Acquity, H-class, Arc)
Reduce Trial-and-Error in HPLC Development
Optimize gradients, pH, temperature and column selection with confidence